Biofield Pharma Private Limited

DOXYGIV-AM (Doxofylline 400 mg + Montelukast 10 mg Tablet)

DOXYGIV-AM is a combination prescription medicine used for the long-term treatment and prevention of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients:

• Doxofylline 400 mg

• Montelukast 10 mg

This combination works by relaxing the airway muscles and reducing inflammation in the lungs, helping improve breathing and prevent asthma symptoms. Below is a detailed explanation in approximately 2000 words covering its composition, mechanism, uses, dosage, benefits, precautions, side effects, and clinical significance.

1. Introduction to Respiratory Diseases

Respiratory diseases like asthma and COPD are chronic conditions that affect the airways and lungs. They are characterized by:

• Narrowing of airways (bronchoconstriction)

• Inflammation of airway lining

• Excess mucus production

• Recurrent episodes of breathlessness, wheezing, chest tightness, and coughing

Asthma, in particular, is a chronic inflammatory disorder of the airways. The inflammation makes the airways highly sensitive to triggers such as dust, smoke, pollen, cold air, and infections.

Management of asthma requires long-term medications that:

• Reduce airway inflammation

• Relax airway muscles

• Prevent exacerbations

• Improve lung function

DOXYGIV-AM is designed to address both airway narrowing and inflammation simultaneously.

2. Composition and Drug Class A. Doxofylline (400 mg)

Doxofylline belongs to the xanthine derivative group. It is chemically related to theophylline but has a better safety profile and fewer side effects.

Drug class:

• Bronchodilator

• Methylxanthine derivative

B. Montelukast (10 mg)

Montelukast is a leukotriene receptor antagonist (LTRA).

Drug class:

• Anti-inflammatory

• Anti-allergic agent

Together, these drugs provide dual-action therapy for chronic airway diseases.

3. Mechanism of Action A. How Doxofylline Works

Doxofylline works primarily by relaxing the smooth muscles in the bronchi (air passages of the lungs).

1. Phosphodiesterase (PDE) Inhibition

Doxofylline inhibits phosphodiesterase enzymes, leading to an increase in cyclic AMP (cAMP) inside airway smooth muscle cells. Increased cAMP results in:

• Relaxation of bronchial muscles

• Widening of airways (bronchodilation)

• Improved airflow

2. Minimal Adenosine Receptor Interaction

Unlike theophylline, doxofylline has limited action on adenosine receptors. This reduces:

• Cardiac side effects

• CNS stimulation

• Gastric irritation

This makes doxofylline safer and better tolerated.

B. How Montelukast Works

Leukotrienes are inflammatory chemicals released by immune cells in response to allergens and triggers.

They cause:

• Airway narrowing

• Swelling of airway lining

• Increased mucus secretion

Montelukast blocks leukotriene receptors (CysLT1 receptors), preventing leukotrienes from exerting their effects. This leads to:

• Reduced inflammation

• Decreased bronchoconstriction

• Fewer asthma attacks

• Reduced allergy symptoms

Additional Information:

• Production Capacity: Fully automated, ISO & USFDA-compliant 600,000 Sq. ft. plant with zero liquid & gas discharge facility
• Delivery Time: 45-60 DAYS
• Packaging Details: Our packaging is designed to ensure maximum product safety, stability, and market appeal. We utilize high-quality raw materials (RM) and USFDA-approved packaging components, making our products ideal for export and third-party manufacturing. Key Features of Our Packaging: ✅ Attractive & Market-Differentiating Designs: Our products come with customizable branding and change parts, allowing businesses to create a distinct identity in the pharma market. ✅ Pharmaceutical-Grade Materials: We use high-density PET bottles, tamper-evident caps, and premium blister foils to maintain product integrity. ✅ Advanced Protection: Our packaging is moisture-resistant, UV-protected, and oxidation-resistant, ensuring longer shelf life and stability. ✅ High-Precision Batch Coding & Labeling: We use laser batch coding, holographic labels, and serialized QR codes for authenticity and traceability. ✅ International Standards for Export: All our packaging materials meet USFDA, EUGMP, and WHO-GMP regulations, ensuring global compliance. Our packaging solutions help PCD Pharma companies, third-party manufacturers, and exporters differentiate their products in highly competitive markets while maintaining the highest pharmaceutical standards.

DOXYGIV-AM is a clinically formulated antimicrobial suspension designed to provide effective treatment for a broad range of bacterial infections in both pediatric and adult patients. Its dual-action formulation ensures rapid infection control while supporting faster recovery and overall health.

Manufactured in a WHO-GMP-certified facility under stringent quality control standards, DOXYGIV-AM ensures high purity, precise dosing, optimal stability, and enhanced patient compliance. It is ideally positioned for PCD Pharma Franchise, third-party manufacturing, and regulated export markets.

How It Works Antibacterial Action

• Targets susceptible bacterial strains responsible for respiratory, urinary, and gastrointestinal infections

• Inhibits bacterial protein synthesis to stop growth and replication

• Provides rapid symptomatic relief and infection control

Supportive Recovery

• Helps reduce fever, inflammation, and discomfort associated with infections

• Promotes overall health and faster recovery

• Suitable for both pediatric and adult patients

Key Features & Benefits

• Broad-spectrum antimicrobial activity

• Clinically effective for respiratory, urinary, and gastrointestinal infections

• Pediatric-friendly suspension with palatable taste

• Accurate dosing for children and adults

• WHO-GMP-certified manufacturing

• Stable, leak-proof packaging for extended shelf life

• Ideal for domestic and export markets

• PCD Pharma Franchise & third-party manufacturing ready

Indications

• Respiratory tract infections

• Urinary tract infections

• Gastrointestinal bacterial infections

• Skin and soft tissue infections

• Pediatric and adult infections caused by susceptible bacteria

Dosage & Administration

• Dose: As directed by the physician

• Pediatric and adult dosing based on age, body weight, and severity of infection

• Shake well before use

• Use provided measuring spoon or cup for accurate dosing

Possible Side Effects (Generally Mild)

• Mild gastrointestinal discomfort (nausea, diarrhea)

• Headache

• Temporary dizziness

• Rare allergic reactions

Why Choose DOXYGIV-AM?

• Clinically proven broad-spectrum antimicrobial therapy

• High-quality API and premium excipients for safety and efficacy

• Strict quality assurance and contamination control

• Pediatric and adult-friendly formulation

• Strong franchise and export potential

Business Opportunities

Ideal for partners seeking:

• Pediatric and adult antimicrobial suspension PCD Franchise

• Third-party manufacturing of broad-spectrum antibacterial suspensions

• WHO-GMP-certified antimicrobial manufacturer

• Export-ready oral antimicrobial formulations

BETERCORT 0.5 is a clinically formulated corticosteroid tablet designed to provide effective relief from inflammatory and allergic conditions. Its potent anti-inflammatory and immunomodulatory action helps control symptoms such as swelling, redness, itching, and pain, improving patient comfort and quality of life.

Manufactured in a WHO-GMP-certified facility under stringent quality control standards, BETERCORT 0.5 ensures high purity, optimal bioavailability, consistent therapeutic performance, and enhanced patient compliance. It is ideally positioned for PCD Pharma Franchise, third-party manufacturing, and regulated export markets.

How It Works Anti-Inflammatory Action

• Reduces inflammation by suppressing the release of pro-inflammatory mediators

• Helps control swelling, redness, and tissue irritation

• Provides relief in both acute and chronic inflammatory conditions

Immunomodulatory Effects

• Modulates immune system responses to prevent excessive reactions

• Reduces allergic symptoms such as itching and rashes

• Supports symptom control in autoimmune and hypersensitivity conditions

Key Features & Benefits

• Clinically effective corticosteroid for inflammation and allergy management

• Rapid relief from swelling, redness, itching, and pain

• Suitable for acute and chronic conditions

• High-quality API and premium excipients for safety and efficacy

• WHO-GMP-certified manufacturing

• Stable packaging ensuring extended shelf life

• Adult-friendly oral tablet for convenient dosing

• Ideal for domestic and export markets

• PCD Pharma Franchise & third-party manufacturing ready

Indications

• Allergic reactions (urticaria, dermatitis, eczema)

• Inflammatory disorders (arthritis, rheumatism, musculoskeletal inflammation)

• Autoimmune conditions requiring corticosteroid therapy

• Acute and chronic hypersensitivity reactions

Dosage & Administration

• Dose: As directed by the physician

• Adult dosing based on condition severity and clinical response

• Swallow whole with water

• Follow prescribed duration for optimal results

• Do not discontinue abruptly without physician guidance

Possible Side Effects (Generally Mild)

• Mild gastrointestinal discomfort (nausea, heartburn)

• Temporary increase in blood sugar levels

• Rare allergic or skin reactions

• Long-term use may require medical supervision

Why Choose BETERCORT 0.5?

• Clinically proven anti-inflammatory and immunomodulatory therapy

• High-quality API and premium excipients for safety and efficacy

• Strict quality assurance and contamination control

• Convenient oral tablet for adult use

• Strong franchise and export potential

Business Opportunities

Ideal for partners seeking:

• Corticosteroid tablet PCD Franchise

• Third-party manufacturing of anti-inflammatory and immunomodulatory tablets

• WHO-GMP-certified manufacturer for adult care formulations

• Export-ready corticosteroid products

Additional Information:

• Production Capacity: Fully automated, ISO & USFDA-compliant 600,000 Sq. ft. plant with zero liquid & gas discharge facility
• Delivery Time: 45-60 DAYS
• Packaging Details: Our packaging is designed to ensure maximum product safety, stability, and market appeal. We utilize high-quality raw materials (RM) and USFDA-approved packaging components, making our products ideal for export and third-party manufacturing. Key Features of Our Packaging: ✅ Attractive & Market-Differentiating Designs: Our products come with customizable branding and change parts, allowing businesses to create a distinct identity in the pharma market. ✅ Pharmaceutical-Grade Materials: We use high-density PET bottles, tamper-evident caps, and premium blister foils to maintain product integrity. ✅ Advanced Protection: Our packaging is moisture-resistant, UV-protected, and oxidation-resistant, ensuring longer shelf life and stability. ✅ High-Precision Batch Coding & Labeling: We use laser batch coding, holographic labels, and serialized QR codes for authenticity and traceability. ✅ International Standards for Export: All our packaging materials meet USFDA, EUGMP, and WHO-GMP regulations, ensuring global compliance. Our packaging solutions help PCD Pharma companies, third-party manufacturers, and exporters differentiate their products in highly competitive markets while maintaining the highest pharmaceutical standards.

VENTAWAY is a clinically formulated bronchodilator tablet designed to provide effective relief from bronchial asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. Its dual-action mechanism helps open airways, reduce bronchospasm, and improve breathing comfort, enhancing overall respiratory health.

Manufactured in a WHO-GMP-certified facility under stringent quality control standards, VENTAWAY ensures high purity, optimal bioavailability, consistent therapeutic performance, and patient-friendly dosing. It is ideally positioned for PCD Pharma Franchise, third-party manufacturing, and regulated export markets.

How It Works Bronchodilator Action

• Relaxes smooth muscles in the airways

• Reduces bronchospasm and airway obstruction

• Improves airflow and oxygen delivery

Anti-Inflammatory & Symptom Relief

• Helps reduce airway inflammation and mucus production

• Relieves wheezing, shortness of breath, and chest tightness

• Supports long-term management of chronic respiratory conditions

Key Features & Benefits

• Clinically proven bronchodilator and anti-asthmatic therapy

• Rapid relief from asthma attacks and bronchospasm

• Supports better lung function and oxygenation

• Suitable for chronic respiratory conditions like COPD and bronchitis

• Adult-friendly oral tablet for convenient dosing

• WHO-GMP-certified manufacturing

• High-quality API and excipients for safety and efficacy

• Stable packaging for extended shelf life

• Ideal for domestic and export markets

• PCD Pharma Franchise & third-party manufacturing ready

Indications

• Bronchial asthma

• Chronic obstructive pulmonary disease (COPD)

• Bronchitis and wheezing disorders

• Allergic respiratory conditions

• Shortness of breath and bronchospasm management

Dosage & Administration

• Dose: As directed by the physician

• Adult dosing based on severity of symptoms and physician recommendation

• Swallow whole with water

• Follow prescribed duration for optimal results

• Not to be used in combination with other bronchodilators without medical supervision

Possible Side Effects (Generally Mild)

• Mild tremors or palpitations

• Headache or dizziness

• Gastrointestinal discomfort (nausea, upset stomach)

• Rare hypersensitivity reactions

Why Choose VENTAWAY?

• Clinically effective bronchodilator for acute and chronic respiratory care

• High-quality API and premium excipients for safety and efficacy

• Strict quality assurance and manufacturing compliance

• Convenient adult-friendly tablet for reliable symptom control

• Strong franchise and export potential

Business Opportunities

Ideal for partners seeking:

• Bronchodilator and anti-asthmatic tablet PCD Franchise

• Third-party manufacturing of respiratory care formulations

• WHO-GMP-certified manufacturer for adult respiratory medicines

• Export-ready asthma and COPD treatment products